WormClassroom

Instructional Materials

Genetics instructional materials

Genetics Research Questions

Geneticists are interested in how genes affect the formation/development of cells/organisms. For instance, PAR (partitioning defect) genes are important in C. elegans cell polarization. The deletion of PAR2, one of the PAR family genes, in a C. elegans zygote will produce two identical daughter cells instead of two unequal sizes daughter cells (AB and P1 cells).

Here is a list of C. elegans genetics research questions to get you start thinking about research in genetics.

Genetics Research: Tools, Procedures & Methodologies

• Crosses: cross between hermaphrodite & male (contribution needed)
• Mutagenesis: use mutagens to generate mutants (contribution needed)
• Screen: search for desired phenotype (contribution needed)
• Gene mapping (contribution needed)
• RNAi (contribution needed)
• C. elegans cultivation

Techniques from cell biology may be used in conjuction with genetic techniques to analyze and understand the consequences of genetic manipulation such as mutagenesis, screen or crosses.

Example Research

• Cell Division
• C. elegans Phenotypes

Research Labs

A list of research labs inquiring into genetics phenomena using C. elegans.