(answers for these questions => only when they are applicable)

Who first introduced (invented) this technique? (a bit history about its discovery)
What is it?
Why is it used (when to use it to produce what consequences? to study what?)?
How does it work? (the mechanism: such as RNAi to block RNA translation)
How is it done? (methodology)
How much time does it take?
Advantage or disadvantage to use such technique in research
An example to illustrate such technique (movies, images and any other resources to accompany the explanation)
More information