WormClassroom

“AceView offers an integrated view of the human, nematode and Arabidopsis genes reconstructed by co-alignment of all publicly available mRNAs and ESTs on the genome sequence.”

A very comprehensive website that covers materials from evolution/development through gene identification by expressed sequence tags to a variety of nematodes.

Its mission is to facilitate genetic research of C. elegans through the production of deletion alleles at specified gene targets.

All about C. elegans genome. This is a good place to look up a gene or a chromosome and to compare them with other species.

Hosted at the University of Minnesota. This site contains links to Worm Breeder’s Gazette (WBG), C. elegans bibliography, C. elegans nomenclature and C. elegans strain list, etc.

The Fire Lab studies how cells respond the introduction of foreign or unwanted genomic materials. One of the interesting experiments done was to inject foreign DNA or RNA into cells and it is not expressed (silencing effect). The major emphasis of the lab is now on the mechanism of RNAi.

This is a powerful site about C. elegans genome sequencing: history, methods and current projects worldwide (contains advanced data).

Gene expression coordination during animal development is what this lab studies. Currently the Hope Lab employs GFP fusion proteins to better understand the organization of gene expression during development time.

A set of tools used for browsing cDNA alignments in the C. elegans genome. There are also links to websites including methods of DNA sequencing, introns, exons or cDNA pasting.

Because of similarities with the human genome, C. elegans may be used to study human pathologies. NemaGENETAG consortium is aiming to create a transposon library because transposons systems may be used for many genome manipulations, such as inserting new sequences.

Note: this link is included as a “legacy” – it has not been updated since 1996. For more recent information on Ronald Plasterk, see his Wikipedia entry.

Their research concentrates on how the genome is protected from mutations and transposons phenomenon. It is not well understood how transposon regulation and mutator genes function and what their role in preventing mutations in the genome is.

Results from RNAi phenotypic analysis of genes in C. elegans can be found.

This lab is interested in cell migration. Researchers are studying the mechanisms that lead a cell to its target and the genes that participate in this guidance.

The genes we share with yeasts, flies, worms and mice: New clues to human health & disease.

Explains the specifics of C.elegans gene naming.